JLR Research


Launched in 2003, JLR's research office is investigating promising new developments and treatments in the field of anesthesiology. As reported by the American Society of Anesthesiologists, some of the greatest advances in surgery and medicine have emerged thanks to anesthesiology's developments in patient monitoring, better anesthetic agents and new drug therapies.

With a goal of continually improving patient care and safety, research in the field is focusing on areas like pain therapy, infection control, organ transplantation and difficult airway management in a variety of subspecialties, including geriatric, obstetric, pediatric, cardiovascular, critical care, ambulatory and neurosurgical anesthesia 

JLR's current research efforts focus on the development of a Perioperative Pain Research Center at Florida Hospital Winter Park which is designed to serve as an internationally-recognized center of excellence in perioperative care of patients undergoing painful surgeries. Since its inception in 2012, the Winter Park research center, a partnership between JLR and Florida Hospital, has launched several key initiatives:

  1. Cadence Pharmaceutical Study - Examining the efficacy of Ofirmev (intravenous acetaminophen) and Robaxin after major orthopaedic surgery. This is a blinded, controlled trial comparing IV Ofirmev/Robaxin to oral Tylenol/Robaxin for 48 hours after total knee surgery. The pilot study, which was a retrospective chart review, was completed recently and powered the clinical trial at 90 patients in each arm. The pilot study was funded by Cadence Pharmaceutical, and they are expecting a proposal for the clinical trial. JLR is coordinating with the director of Florida Hospital's ORA Office of Research Administration (ORA), Dr. Dolske.
  2. Pacira Pharmaceutical Trials - Phase III and IV trials evaluating Exparel (liposomal encapsulated bupivicaine) for use in regional anesthesia.
  3. FIRE (Focused Individualized Research Experience) Projects - This is a mandatory program for first-year medical students at the University of Central Florida College of Medicine. Last year, JLR presented its chart review study to the class of 2015, and incorporated medical students. JLR hopes to grow FIRE student involvement in its research program.
  4. Regional Anesthesia Registry Part of a five-year plan, JLR hopes to establish the largest such registry in the world that collects this type of data from a single institution.

Related Staff

Thomas Looke, MD

Director of Research and Co-director of the Division of Regional Anesthesia and Acute Pain Management

Thomas Looke, MD, has served as JLR’s director of research since 2003 and is currently working with the leadership team at Florida Hospital Winter Park to establish a Perioperative Pain Research Center at that facility. Throughout his career, Dr. Looke has authored numerous protocols that improved patient safety and satisfaction, and has served in a variety of leadership positions within JLR and Florida Hospital, including Chief of Regional Anesthesia Services for Florida Hospital, authoring the regional anesthesia protocols used in the Orthopaedic Center of Excellence. He was awarded the Florida Hospital Medical Staff Award for Excellence in 2007 for his success in improving total joint surgery patient outcomes and satisfaction through improved regional anesthesia services. Dr. Looke joined JLR in 2001 after completing medical school and his anesthesiology residency training at the University of Florida. He graduated from the Naval Academy in 1983 and served as a combat officer and engineer in the U.S. Navy prior to entering medical school. While in the Navy, he also earned a master’s degree in electrical engineering from Caltech in Pasadena, California, in 1984, and a PhD in the same field from Queen’s University in Ontario, Canada, in 1992.

JLR Medical Group

851 Trafalgar Court, Suite 200E
Maitland, Florida 32751

Phone: 407-667-0444

Toll Free: 800-331-2104
Fax: 407-667-4338

For employment opportunities as an anesthesiologist
or a CRNA, please visit the careers page.

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